Seconal Sodium
€370.00 – €1,250.00
Seconal Sodium, also known as Secobarbital Sodium, is a barbiturate medication used primarily as a sedative and hypnotic. It was once commonly prescribed for the short-term treatment of insomnia, as well as for anxiety and as a preoperative sedative. Secobarbital is classified as a central nervous system (CNS) depressant, which means it works by slowing down brain activity and producing a calming effect.
Chemical & Physical Properties:
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Chemical Name: Secobarbital Sodium
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Brand Names: Seconal Sodium, Secobarbital Sodium
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Molecular Formula: C12H17N2NaO3
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Molecular Weight: 258.27 g/mol
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Appearance: Typically available as yellow capsules or oral solution.
Primary Uses:
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Insomnia Treatment: Secobarbital sodium is used to help patients who have trouble falling or staying asleep. It works by inducing sleep quickly and effectively.
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Anxiolytic (Anti-anxiety): It can be prescribed for patients experiencing anxiety, especially when other anti-anxiety medications are not effective.
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Preoperative Sedation: Secobarbital is used to prepare patients for surgery by inducing sedation and reducing anxiety prior to procedures.
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Seizure Control (Emergency use): In certain emergency situations, secobarbital may be used to control seizures, particularly when other medications are ineffective.
Mechanism of Action:
Secobarbital works by enhancing the activity of GABA (gamma-aminobutyric acid) in the brain, which is an inhibitory neurotransmitter. This increases the calming effect of GABA and suppresses brain activity, leading to sedation and sleep induction. As a result, it reduces anxiety, induces sleep, and can be used in emergency situations for seizure control.
Side Effects and Risks:
Although secobarbital is effective for its intended uses, it carries significant risks due to its CNS depressant properties. These risks include:
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Respiratory Depression: Like other barbiturates, secobarbital can suppress breathing, especially at higher doses or when combined with other CNS depressants (such as alcohol, benzodiazepines, or opioids). This can lead to hypoxia (lack of oxygen) and potentially fatal respiratory failure.
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Cognitive and Motor Impairment: Secobarbital can impair memory, coordination, and judgment, making tasks such as driving, operating machinery, or making important decisions dangerous.
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Dependence and Addiction: Secobarbital has the potential for physical dependence and tolerance with prolonged use, meaning the body requires higher doses to achieve the same effect. Sudden discontinuation of the medication can lead to withdrawal symptoms, including anxiety, tremors, seizures, and agitation.
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Overdose: An overdose of secobarbital can lead to coma, cardiovascular collapse, hypotension, respiratory depression, and death. Overdose is particularly dangerous when combined with other CNS depressants.
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Drowsiness and Sedation: While this is expected from the medication, the excessive drowsiness or prolonged sedation can interfere with daily functioning and significantly impact quality of life.
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