Butalbital pills
€345.00 – €1,100.00
Butalbital is a barbiturate medication primarily used to treat tension headaches and migraines. It is commonly combined with acetaminophen (Tylenol) and caffeine to enhance its effectiveness, and the combination is marketed under brand names like Fioricet and Fiorinal. Butalbital works by depressing the central nervous system (CNS), which helps to relieve pain and reduce anxiety associated with headaches.
Chemical & Physical Properties:
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Chemical Name: 5-(1,3-dimethylbutyl)-5-phenylbarbituric acid
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Molecular Formula: C11H16N2O3
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Molecular Weight: 224.26 g/mol
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Appearance: Butalbital is typically found in pill or tablet form.
Primary Uses:
Butalbital is used primarily for:
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Tension headaches: It helps reduce the severity of headaches caused by stress or muscle tension.
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Migraine headaches: When combined with other medications like acetaminophen and caffeine, Butalbital can be used to treat migraines, especially when other treatments are not effective.
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Anxiety: Butalbital may also have mild anxiolytic (anti-anxiety) effects due to its CNS depressant properties.
Mechanism of Action:
Butalbital works by enhancing the effects of GABA (gamma-aminobutyric acid), a neurotransmitter that inhibits brain activity. This results in a sedative effect that can reduce pain, muscle tension, and anxiety. When combined with acetaminophen (which has analgesic effects) and caffeine (which helps increase the effectiveness of the other ingredients), it provides a more comprehensive approach to managing headaches.
Side Effects and Risks:
While Butalbital can be effective for treating headaches, it also carries several side effects and health risks, including:
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Addiction and Dependence: Butalbital is a barbiturate, which means it has a high potential for abuse and dependence. Long-term use can lead to tolerance, meaning higher doses are needed to achieve the same effect.
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Overdose Risk: Like other barbiturates, Butalbital can be dangerous in large quantities and can lead to respiratory depression, coma, or even death. Overdose risk increases when combined with other CNS depressants, such as alcohol or benzodiazepines.
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Cognitive Impairment: Regular use of Butalbital can impair memory, judgment, and coordination, making tasks like driving dangerous.
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Withdrawal Symptoms: Abrupt discontinuation after long-term use can cause withdrawal symptoms, such as anxiety, tremors, and seizures.
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Drowsiness and Dizziness: As a sedative, Butalbital may cause drowsiness, dizziness, and a general feeling of lethargy.
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Risk of Drug Interactions: Butalbital can interact with several other medications, potentially leading to dangerous side effects. It should be used cautiously with other CNS depressants.
Alternatives:
Due to the addiction potential and side effects associated with barbiturates, Butalbital-containing medications are less commonly prescribed today. Safer alternatives for treating headaches include:
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NSAIDs like ibuprofen or naproxen for pain relief.
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Triptans (like sumatriptan) for migraine relief.
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Over-the-counter pain relievers such as acetaminophen or aspirin.
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Prescription medications like beta-blockers, antidepressants, or anticonvulsants for chronic migraine management.
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