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  • JWH-018 powder is a synthetic cannabinoid that acts as a full agonist at CB1 and CB2 receptors, mimicking the effects of THC (tetrahydrocannabinol), the primary psychoactive compound in cannabis. It was one of the first synthetic cannabinoids used in “Spice” or “K2” herbal smoking blends, which were marketed as legal alternatives to cannabis. However, JWH-018 is much more potent than THC and has been linked to severe side effects and health risks.

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